Here are the other two safety equipment articles I've written:
Choosing a respirator | Soapy Stuff
Eye protection | Soapy Stuff
Unless you are sensitive to fragrance, a respirator is useful mostly for making lye solution -- right when the solution is really hot and steamy. If you have good ventilation (like working under the hood of your stove), a respirator might not be needed even then if you don't hang your nose over the lye container and keep the container lightly covered as much as possible to keep the vapors where they belong -- IN the container rather than floating around the open air.
If you're sensitive to fragrances, you should probably be wearing a respirator the entire time you're making soap or handling the freshly made soap -- any time when the scent is detectable. The type of respirator for protecting against fragrance is different than that for dust and vapors -- read my article about respirators for more. A quote from that article --
Respirators are not the only solution nor are they always the best solution for controlling your exposure to dusts, mists, and volatile chemicals. It is a much better approach to first reduce how much of these pollutants get into the air in your home or workshop and then use a respirator as insurance. Ways to reduce air pollution in your home or workshop when soaping or making B&B products --
Work with lye, fragrances, and dusty ingredients outdoors in good weather
Using effective ventilation in your work area (such as a running stove hood that vents outdoors)
Keeping your lye container lightly covered at all times, but especially while the solution is hot
Wearing an effective respirator as a final bit of insurance
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There is no one safety goggle or glasses that is best for everyone -- fit and comfort are so individual. Problem with buying safety gear at the local "big box" store is most of the safety products in these stores are chosen for men with their larger physiques.
For example, I keep a large box of disposable foam ear plugs in my shop for everyone to use when operating machinery. I didn't realize until I shopped at a safety equipment store that these plugs come in small and medium sizes. Us girls really appreciate the smaller ones -- they go easily into the ear canal and stay put.