I'm horrible, I admit it.
I don't use gloves, goggles, or any protective gear. I mix in short sleeves and shorts, but at least I always have shoes on.
I mix mine up ahead of time. I mix usually 3 pounds of lye at one time then store it in an air tight plastic jug well labeled.
I understand the danger of working with lye, but I also realize I've been cleaning my drains for years and never donned hazmat gear to do that so why start now ? As long as I'm careful it should be ok and like another poster stated, I'd prefer to know immediately if I do spill some on me.